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Fish Collagen

Peptan Fish Collagen
by Rousselot in France

180 Gram
Product Code: RFC1154
Retail Price: $69.95 Online Price: $49.95

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Fish Hydrolyzed Collagen 180 grams
Higher Purity with Smallest 2000Da

A revolutionary youth and beauty enhancing complex powder drink works on the deep, structural layer of the skin and the dermis to increase the strength, elasticity and hydration levels of the skin.

Collagen provides the vital building blocks needed for increasing the mechanical strength of the skin. Hyaluronic acid hydrates the dermis which promotes elasticity for wrinkle prevention. Extract of wild Mexican yam has benefits to maintain perpetual youth. These nutrients work synergistically in the dermal layer to keep your skin looking younger, longer.  

Enhancing beauty from within

Having healthy skin inside and out is a growing desire among all consumers (and not just women). Your skin is the primary sign of everyday health but it is also the first indicator of age. As the world population ages, there is growing interest in skin health solutions.

Products known as 'nutricosmetics' – nutritional supplements which support and strengthen the skin's structure with more than just superficial effects – are increasingly in demand.                                           

Rousselot Fish Collagen is the optimal nutritional oral skin solution

  • Promotes younger looking skin
  • Improves skin moisture level
  • Improves skin smoothness
  • Prevents formation of deep-winkles
  • Improves skin suppleness

Scientifically Proven

Positive findings from two scientific studies give Peptan® all-important credibility for the nutricosmetics industry. Taken daily, for up to 12 weeks, clinical studies show that regular intake of Peptan® improves the underlying condition and structure of your skin.


Moisturizing effect


Anti-aging effect


Joint & Bone Health

As the population ages, the drawbacks of aging have been brought sharply into focus. Two of the major health concerns are osteoarthritis and osteopenia (bone loss), the leading causes of pain and disability. It is today known that Peptan® can help in the prevention of both these age-related conditions.

Bone Health

In healthy bone function, there is a constant regeneration of tissue, ensuring that the bone remains strong. Osteopenia results when an imbalance occurs between the normal breakdown and formation of bone in the body, resulting in low bone mass and loss of bone tissue.

Peptan® - The bioactive ingredient for bone health

Collagen, which represents 90% of organic bone mass, has been shown to trigger bone formation and thus help prevent bone disease.
Peptan® helps keep your bones healthy and strong.

Joint Health

A joint is the point of connection between two bones. Osteoarthritis, the most common form of arthritis, is a chronic degeneration of the joints and is today considered by the World Health Organization to be one of the ten main diseases in developed countries. For sufferers, the quality-of-life consequences are significant as 80% face limited movement and 25% cannot perform basic day-to-day activities.

Peptan® - The bioactive ingredient that reduces joint pain

Over 90% of orally administered Peptan® is absorbed and a large part is accumulated in the cartilage as early as 12 hours after ingestion.

Peptan® reduces joint pain and helps prevent joint degeneration.

Created with Raphaël Created with Raphaël



**Daily value not established.

Other Ingredients:Natural French Vanilla Flavor.

Contains no artificial flavors or preservatives. Keep in a cool dry place tightly closed.

Safety sealed for your protection. Do not use if inner seal is broken or missing.




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 Direction: As a dietary supplement, take 1-2 tablespoons once a day on an empty stomach. Stir in hot water, milk or coffee for 1-2 minutes. Drink and Enjoy it.










Peptan Collagen Peptides

The Peptan® story began in the early 2000s, when scientists at Rousselot discovered a specific blend of natural proteins (enzymes) that transform native collagen molecules into collagen peptides while preserving the neutral organoleptic properties (odor and taste) and white color of the collagen peptides powder.

Spurred by this realization, Rousselot began developing a full range of collagen peptides, to be marketed under the brand name Peptan®.

Peptan collagen peptides are made from fish skin, pigskin or bovine hide from stock farm-bred for human consumption. Rousselot collagens are produced from selected, high-quality raw materials subject to continuous rigorous checks on safety and origin.

Rousselot Research & Development teams called on scientific experts to verify the health benefits associated with collagen peptides. As the findings emerged, Rousselot teams became more and more convinced of the unique properties of Peptan collagen peptides. Several comprehensive studies were subsequently published in recognized scientific journals. ||read more||

Peptide is derived from the Greek word πεπτός, which means “digested”. Peptides are fragment of proteins.

Peptan® are type-I collagen peptides and have the same amino-acid content as that found in human bones and skin. Peptan® is a high purity, natural bioactive ingredient containing more than 97% protein, with no fat or carbohydrates. Peptan® is supplied in a form that is easy to use and digest, as shown by scientific analysis.

Rigorous research findings and unmatched quality make Peptan® a truly differentiated ingredient. Numerous studies have been published and reviewed over the past decade endorsing its safety and efficacy.

When it comes to quality, safety and clinical evidence, the scientific qualities of Peptan® remain unparalleled.

Peptan® is produced using GMP (Good Manufacturing Practice) and ISO 9001 certified manufacturing facilities. As far as safety is concerned, collagen peptide is without doubt one of the world's best studied foodstuffs and it has been confirmed safe by the World Health Organization (WHO).

Peptan® is Kosher and Halal certified and has earned Generally Regarded as Safe (GRAS) status in the USA.

Peptan® is a registered trademark (registration is ongoing worldwide).

Peptan® Health

As the population ages, the drawbacks of aging are becoming more apparent. Osteoarthritis and osteopenia, two of the major health concerns, are among the leading causes of pain and disability.
It is now well known that collagen peptides can help to maintain bone and joint health to prevent osteopenia and osteoarthritis.

Collagen Peptides for Joint and Bone Health
The world health market is pushed by consumer concern over diseases and pulled by consumer fascination with well-being. The population is getting older, and growing old has its drawbacks: two of the major health concerns are osteoarthritis and osteoporosis, which are leading causes of disability. There is growing scientific evidence that Collagen Peptides can promote joint and bone health.

It is now well known that Collagen Peptides may help to maintain bone and joint health to prevent osteopenia (low bone mass) and osteoarthritis. ||read more||

According to the World Health Organiza¬tion (WHO), osteopenia is used to describe individuals who have a low bone mass and some increased risk of fracture. Their bone mass is not so low that they are deemed to have osteoporosis.

Osteoarthritis is a joint affliction characterized by degenerative lesions of joint cartilage.
According to the World Health Organization, after the age of 50, 10% of men and 18% of women suffer from osteoarthritis.

Dynamic growth on the bone & joint health market
In 2009, Rousselot has received Frost & Sullivan Growth Strategy Excellence Award for its success within the European bone and joint health ingredients market.
Quality, strong market adequacy of Peptan®, as well as continuous efforts to enhance its recognition have been the basis of Rousselot success in this sector.



Benefits of Peptan® on Joint and Bone health

Peptan® Health is a natural product, a unique collection of peptides that is nearly identical to the collagen found in the bones and joints in the body.

To fight against osteopenia, different formulations can be suggested in order to reach 10g of Peptan® per day which is the recommended daily intake. A synergetic effect can be found by using a blend of other nutrients known to have a positive effect on bones such as Vitamin D and Bio-available Calcium

Peptan® is easy to integrate into nutraceuticals which prevent joint symptoms such as pain and stiffness. It can also be used as a complement with glucosamine and chondroïtine sulfate in some applications.

Peptan® is flavorless, odorless, colorless and highly soluble, making it easy to use as a daily nutritional supplement for maintaining joint and bone health.

Scientifically Proven


It has been scientifically proven that taking 10g a day of Collagen Peptides for a period of 4 to 24 weeks will increase bone mass density and have a positive effect on relieving joint pain.

In 2001, Mizuno and Kuboki demonstrated that the endogenous production of Collagen by bone cells is stimulated by collagen peptides which leads to some elements on the mechanism.

Studies conducted by Rousselot and published* in " Bone" journal confirmed the effects of PeptanTM on bone metabolism and highlight its mechanism of action.

In response to consumer concerns regarding long-term bone health, Rousselot has carried out, for several years now, many studies to demonstrate that an oral intake of PeptanTM may have a positive impact on osteopenia.

Bone is a living dynamic metabolic system that relies on a maintained balance between bone formation and bone resorption. Cells called osteoblasts make bone while cells called osteoclasts resorb it. An imbalance may lead to osteopenia, a condition where the density and quality of bone is reduced.

Researchers conducted in vitro studies, and highlighted that PeptanTM in bone cell culture induced a better differentiation of osteoblasts. Those positive results have then been confirmed in vivo.

Animals were divided into three groups: a control group (non ovariectomized), a group of ovariectomized mice, both fed with a normal diet and a group of ovariectomized mice that received a diet containing PeptanTM. After 12 weeks, the BMD of the group fed with PeptanTMis not significantly different from the BMD of control group. On the contrary the BMD of ovariectomized mice not fed with PeptanTM is lower.

Confirmation of cbenefits on bone health has been obtained by the measures of Carboxy Terminal Telopeptide (CTX), a usual marker of bone resorption. CTX is significantly lower in mice fed with Peptan® indicating that bone resorption is reduced.

Researchers conclude that PeptanTM may restore bone density by stimulating osteoblast growth and differentiation. This demonstrates the interest of PeptanTM as a bioactive ingredient to help preventing bone loss during aging.

*Hydrolyzed collagen improves bone metabolism and biomechanical parameters in ovariectomized mice: an in vitro and in vivo study. Guillerminet F., Beaupied H., Fabien-Soulé V., Tomé D., Benhamou C-L., Roux C., Blais A.. Bone (2009).


The effect of Collagen Peptides on the preservation of joint health is more significant for patients suffering more severe symptoms. It was demonstrated in 2003 by Oesser S. (Cell Tissue Res, 311: 393-399) that the ingestion of Collagen Peptides may stimulate the endogenous production of collagen, providing the pool of amino-acids and peptides useful for collagen synthesis by the chondrocytes (cartilage cells).


New video on Peptan® for bone and joint health

Stay active, Stay healthy....!



Peptan® Beauty

Enhancing Beauty from Within with Collagen Peptides

What is good on the inside reflects how the outside appears to the world. It’s not just women who have a desire for healthy skin. Skin is the primary visual indicator of everyday health and also presents external aging symptoms. As the population is getting older, there has been increasing interest in the skin health market.

Products called “Nutricosmetics”, which have more than a superficial effect, are increasing sharply in number. In addition to conventional skin care with topical applications, the “Beauty from Within” trend has become more popular.



Peptan®, a key nutrient for skin beauty. Peptan® are bioactive peptides highly concentrated in skin’s essential amino-acids which the body can easily absorb on a daily basis.

Peptan® may stimulate the production of collagen by the skin cells themselves and help maintain youthful, vibrant skin and fight the skin’s continuous aging process by re-densifying the dermis.

Easy to use and to integrate
Peptan® are well suited to be used as powder products or in capsules in cosmeceutical applications. This benefits “from inside” to the beauty of skin.
Peptan® is flavorless, odorless, colorless and highly soluble, making it easy to use as a daily nutricosmetic product.


Scientifically Proven


The efficacy of PeptanTM on skin health has been shown by two double-blind placebo-control trials of oral supplementation in France and in Japan.

In France, 47 women aged from 35 to 55 were select by DERMSCAN in Lyon, to participate in a study on skin condition, during 12 weeks in winter. At the same time in Japan, 33 women aged from 40 to 59 were select by SOUKEN in Tokyo, for a period of 8 weeks.

In both studies, women had to ingest either 10g of PeptanTM or 10g of dextrins as placebo everyday. Anti-aging and moisturizing effect of Peptan were measured.

Concerning the moisturizing effect, which was assessed by the measure of the cutaneous hydration, 91% of Peptan® volunteers saw their skin hydration level increased. Skin hydration level was significantly improved compared to the placebo after 8 weeks.

Concerning the anti-aging effect, the number of micro-relief furrows significantly decreases with Peptan® after 12 weeks. Peptan® has been also shown to significantly prevent the number of deep wrinkles, and to increase the skin suppleness.

Moroever, women themselves noticed improvements: they felt an improvement of the hydration, the brightness, the tonicity and the suppleness of their skin with Peptan®. Finally, the make-up application seemed them easier.

Explanations of the mechanism of action of Collagen Peptides on skin are available in literature. According to researchers, when type 1 collagens are digested by collagenase, the resulting peptides are chemoattractans for fibroblasts, the main cells of the skin, and the producers of collagen. Collagen peptides may act as messenger and trigger the synthesis and reorganization of new collagen fibers by stimulating fibroblast cells*. Furthermore, some studies show that Collagen Peptides may improve the mechanical strength of the skin by increasing decorin ratio, proteins which interact with collagen and influences collagen fibrillogenesis, thus regulating excessive bundle-like aggregation of collagen**.

* Postlethwaite, A.E, Seyer, J.M. and Kang, A.H. 1978. Chemotactic attraction of human fibroblasts to type I, II, and III collagens and collagen-derived peptides. Proceedings of the National Academy of Sciences of the United States of America, 75(2):871-875.

** Matsuda, N., Koyama, Y., Hosaka, Y., Ueda, H., Watanabe, T., Araya, T., Irie, S. and Takehana, K. 2006. Effects of ingestion of collagen peptide on collagen fibrils and glycosaminoglycans in the dermis. Journal of nutritional science and vitaminology, 52:211-215.

For more informations on these studies, please contact us.

Step 1

Oral intake of Peptan® Collagen Peptides.

Step 2

Peptan® is easily digested in small peptides and bioavailable.

Step 3

Peptan® is distributed through the blood circulation to the body.

Step 4

Skin, damaged by the time, is repaired by the action of Peptan®, endogenous collagen production is stimulated.



New video on Peptan® Beauty

“Since the dawn of time, people have wanted to stay healthy, young and beautiful…”



Peptan® Cosmetic

Collagen peptides for effective skincare and personal care

Collagen is one of the most abundant scleroprotein of the connective tissue occurring as fibres accounting for 70 to 80% of skin dry weight. It is the main structure element of the skin and, therefore, largely responsible for its characteristic properties.

Peptan® Cosmetic are pure natural type I collagen peptides, preservative-free and easy to formulate in all your cosmetic applications.

The Peptan® Cosmetic peptide is based on a sequence (GLY-PRO –X or GLY-HYPRO –X) which is naturally present in the dermis and contains 18 different amino acids, including glycine, proline, and hydroxyproline in particular ; these three molecules account for almost 50% of all the amino acids present.

From applications in medicine, it is known that collagen accelerates the healing of skin wounds and the spontaneous reepithelization of the skin.

Used in cosmetic preparations for its water binding potential and anti-aging benefits, collagen helps to promote skin hydration and delays skin aging.


Peptan® Cosmetic range

Peptan® Cosmetic is an exceptionally versatile, natural material offering a unique combination of functional and sensory benefits. Our tailored offering includes Collagen peptides that can help you to create innovative solutions, high-end products adapted to your specific cosmetic needs.

• Moisture Retention: Peptan® MR / Peptan® MR marine

Peptan® MR is a natural biopolymer with film-forming properties which maintains the moisture balance of the skin and supplies skin with important amino-acids.

• Skin Regeneration: Peptan® SR marine

Peptan® SR marine is an active peptide of marine origin providing the amino acids required for the correct functioning of skin cells. It boosts fibroblast proliferation and favors the synthesis of the major structural collagen molecule of the dermis, thus preserving its structural organization. It also protects against free radicals, limiting their aging effect.


Scientifically Proven

3-step skin regeneration collagen peptides

   1. Stimulates fibroblast proliferation
   2. Boosts collagen synthesis
   3. Protects against oxidative stress

Peptan® SR marine is tailored for skin care where anti aging action is desired.

In vitro tests have proven that Peptan®SR marine activates collagen synthesis by fibroblasts. It restores the three dimensional architecture of the dermis, increasing the volume of this tissue and providing it with cohesion and tonicity. Its effects on the extracellularmatrix of the dermis thus counteract the loss of firmness that occurs over time and eventually leads to wrinkles.

Peptan®SR marine thus has an antioxidant effect providing protection against agents generating free radicals.


Peptan® Nutrition

Peptan® Nutrition
A High Quality Protein in Weight Management and Sports Nutrition

Overweight Facts
The World Health Organization (2003) estimates that there are more than 1 billion overweight adults, including at least 300 million obese in the world.
In Europe, there are approximately 200 million overweight people. In the USA, the estimate reaches 127 million overweight adults, 60 million of them considered as obese and 9 million severely obese.

A high quality protein for balanced diets
Proteins such as collagen peptides can contribute to a balanced diet and help maintain body weight. Protein enriched diets have demonstrated that they help to maintain body weight, in particular due to their “satieting” effect.


A natural product, Peptan® is an incomparable source of protein for weight management. It provides a feeling of fullness that helps maintain weight.

Peptan® brings few calories

3.60 kcalories / 1g of Peptan™

Peptan™ contains:

  • No fat
  • No cholesterol
  • No carbohydrates


90% (97% on dry weight)





Mineral salts




Peptan® is easy to integrate into nutritional products:
is tasteless, odorless, colorless, and highly soluble, making it easy to use in daily nutritional products for a healthy balanced diet. It can be used blended or not with other proteins.

Scientifically Proven


Rousselot has demonstrated that Peptan® can be used to increase the protein content of food products to help people to maintain their weight and look after their health.
Experiments with Peptan® have been carried out on rats at the Physiology of Nutrition and Feeding Behavior Laboratory of INRA-INAPG (Paris, France). Rats were fed with a high protein diet (50% protein). The source of the protein was Peptan® ’s (fish, bovine and porcine origins) and results here compared to those of a dairy protein (milk concentrate with 85% proteins).
Measured after 24 days, the weights of the animals were significantly lower with the three Peptan® than with the standard dairy protein.

This study demonstrated that Peptan® can have a rapid and significant impact in decreasing the weight of the test animals.
The positive effect of Peptan® was also demonstrated with a diet containing a normal protein level (14%) and blended with other source of proteins.

New video on Peptan® for nutrition

The building blocks for balanced nutrition



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